Transition phenomena induced by internal noise and the discreteness
نویسنده
چکیده
We study a simple chemical reaction system and effects of the internal noise. Although stochastic differential equations are often used in order to study the fluctuations, they can not treat the discreteness in the number of components (molecules, individuals, and so on) because they are based on the continuum approximation which is justified by the large system size. The discreteness of components would not be negligible when we treat the system with small size, such as biochemical reactions in a cell. To elucidate the effects of such discreteness, we propose a simple chemical reaction system, and show that the internal noise and the molecular discreteness cause an anticipated transition phenomenon. The transition phenomenon is characterized by the change of the number of peaks in the stationary probability distribution. The transition point is analytically determined by using a random walk model. PACS. 05.40.-a Fluctuation phenomena, random processes, noise, and Brownian motion – 02.50.Ey Stochastic processes – 87.16.-b Subcellular structure and processes
منابع مشابه
Discreteness-induced transitions in multibody reaction systems.
A decrease in system size can induce qualitatively different behavior compared to the macroscopic behavior of the corresponding large-size system. The mechanisms of this transition, which is known as the small-size transition, can be attributed to either a relative increase in the noise intensity or to the discreteness of the state space due to the small system size. The former mechanism has be...
متن کاملLow Dropout Based Noise Minimization of Active Mode Power Gated Circuit
Power gating technique reduces leakage power in the circuit. However, power gating leads to large voltage fluctuation on the power rail during power gating mode to active mode due to the package inductance in the Printed Circuit Board. This voltage fluctuation may cause unwanted transitions in neighboring circuits. In this work, a power gating architecture is developed for minimizing power in a...
متن کاملTheoretical analysis of discreteness-induced transition in autocatalytic reaction dynamics.
Transitions in the qualitative behavior of chemical reaction dynamics with a decrease in molecule number have attracted much attention. Here, a method based on a Markov process with a tridiagonal transition matrix is applied to the analysis of this transition in reaction dynamics. The transition to bistability due to the small-number effect and the mean switching time between the bistable state...
متن کاملThe Effect of Celecoxib, a Cyclooxygenase-2 Inhibitor on Noise- Induced Hearing Loss
Objective(s): Noise-induced hearing loss (NIHL) is the major cause of acquired hearing loss. Celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, is a non- steroidal anti- inflammatory drug (NSAID) with known antioxidant and antineoplastic activity. Therefore, we monitored the extent of temporary noise- induced threshold shifts (TTS) and cochlear damage caused by high level 4- kHz noise exposure t...
متن کاملPreconditioning by the inhalation of pure oxygen protects rat’s cochlear function against noise-induced hearing loss
Background: Occupational noise-induced hearing loss (ONIHL) is a hearing disorder that affects workers all over the world. Preconditioning with several mild or less potent stressors will effectively prevent the development of noise-induced hearing loss. This study investigated the possible preventive effects of normobaric hyperoxia preconditioning on preventing the noise-induced hearing impairm...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2008